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  • Poly(vinylpyrrolidone)-Iodine complex

  • Poly(vinylpyrrolidone)-Iodine complex

    Catalog Number
    ACM25655418-1
    CAS Number
    25655-41-8
    Product Name
    Poly(vinylpyrrolidone)-Iodine complex
    Category
    Hydrophilic Polymers; Polymers
    Description
    DryPowder;YELLOW-TO-BROWN HYGROSCOPIC POWDER.
    IUPAC Name
    1-ethenylpyrrolidin-2-one;molecular iodine
    Molecular Weight
    364.95g/mol
    Molecular Formula
    C6H9I2NO
    Canonical SMILES
    C=CN1CCCC1=O.II
    InChI
    InChI=1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
    InChI Key
    CPKVUHPKYQGHMW-UHFFFAOYSA-N
    Solubility
    Soluble in water;Soluble in alcohol; practically insoluble in chloroform, carbon tetrachloride, ether, solvent hexane, acetone.;Practically insoluble in acetone, and light petroleum.;Solubility in water: good
    Application
    The Poly(vinylpyrrolidone)-Iodine complex (PVP-I) serves as a versatile antiseptic agent with extensive applications in medical and research settings. By forming a slow-release iodine formulation, it effectively iodinates lipids and oxidizes cellular compounds such as tyrosine side chains, which are crucial in microbial decontamination and inactivation of viruses. PVP-I is employed as a topical antiseptic for preventing infections in wounds during surgery, as well as treating skin and mucous membrane infections. It is also utilized as an aerosol and has been studied for enhancing the solubility of carbon nanotubes in water. Additionally, PVP-I is used in first aid for minor cuts, grazes, burns, abrasions, and blisters, making it an essential component in surgical scrubs and pre- and post-operative skin cleansing. The complex is characterized by its broad microbicidal spectrum, providing effective protection against bacteria, fungi, viruses, protozoa, and yeasts.
    Color/Form
    Yellowish-brown amorphous hygroscopic powder
    Complexity
    120
    Covalently-Bonded Unit Count
    2
    EC Number
    607-771-8;918-309-2;924-458-4
    Exact Mass
    364.87736g/mol
    Formal Charge
    0
    Heavy Atom Count
    10
    ICSC Number
    1471
    MeSH Entry Terms
    Alphadine;Alphadines;Betadine;Betadines;Betaisodona;Disadine;Disadines;Isodine;Isodines;Pharmadine;Pharmadines;Polyvinylpyrrolidone Iodine;Polyvinylpyrrolidone Iodines;Povidone Iodine;Povidone-Iodine;Povidone-Iodines;Providine;Providines;PVP Iodine;PVP-I;PVP-Iodine;PVP-Iodines
    Monoisotopic Mass
    364.87736g/mol
    NSC Number
    26245;28655
    Odor
    A slight characteristic odor
    Other Experimental
    Solutions do not give the familiar starch test when freshly prepared.
    Rotatable Bond Count
    1
    Stability
    Stable under recommended storage conditions.
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