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  • Poly(2-ethyl-2-oxazoline)

  • Poly(2-ethyl-2-oxazoline)

    Catalog Number
    ACM25805178-7
    CAS Number
    25805-17-8
    Product Name
    Poly(2-ethyl-2-oxazoline)
    Structure
    Category
    Hydrophilic Polymers; Polymers
    IUPAC Name
    2-ethyl-4,5-dihydro-1,3-oxazole
    Molecular Weight
    99.13g/mol
    Molecular Formula
    C5H9NO
    Canonical SMILES
    CCC1=NCCO1
    InChI
    InChI=1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3
    InChI Key
    NYEZZYQZRQDLEH-UHFFFAOYSA-N
    Melting Point
    -62°C
    Flash Point
    29.4°C
    Density
    1.05 g/cm³
    Appearance
    Off-white solid
    Application
    Poly(2-ethyl-2-oxazoline) serves as a versatile and innovative polymer due to its unique properties and applications. This amorphous, water-soluble polymer is known for its excellent temperature stability and biocompatibility. Research led by Jordan and team has demonstrated that it does not accumulate in tissues and is rapidly cleared from the bloodstream, making it a suitable candidate for medical applications. It is increasingly gaining attention as a potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone) due to its end-group modification capability, which allows for effective conjugation with peptides and serves as a viable alternative to poly(ethylene glycol) for the conjugation of proteins and small drugs. Additionally, Poly(2-ethyl-2-oxazoline) is utilized as an adhesion promoter in coatings and is highly effective as a heat sealing agent and remoistenable hot-melt adhesive. Its compatibility with solvents such as acetone, DMF, ethanol, MEK, methanol, methylene chloride, THF, and water further enhances its utility across various industrial and pharmaceutical applications.
    Assay
    0.99
    Complexity
    88.1
    Covalently-Bonded Unit Count
    1
    EC Number
    233-912-4
    Exact Mass
    99.068414g/mol
    Formal Charge
    0
    Heavy Atom Count
    7
    MDL Number
    MFCD00134377
    MeSH Entry Terms
    2-ethyl-2-oxazoline
    Monoisotopic Mass
    99.068414g/mol
    NSC Number
    136557
    Packaging
    100 g
    Refractive Index
    n20/D 1.52
    Rotatable Bond Count
    1
    UNII
    B8CD92T4P5
    XLogP3
    0.3
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