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Poly(2-ethyl-2-oxazoline)

Catalog Number
ACM25805178-7
CAS Number
25805-17-8
Product Name
Poly(2-ethyl-2-oxazoline)
Structure
Category
Hydrophilic Polymers; Polymers
IUPAC Name
2-ethyl-4,5-dihydro-1,3-oxazole
Molecular Weight
99.13g/mol
Molecular Formula
C5H9NO
Canonical SMILES
CCC1=NCCO1
InChI
InChI=1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3
InChI Key
NYEZZYQZRQDLEH-UHFFFAOYSA-N
Melting Point
-62°C
Flash Point
29.4°C
Density
1.05 g/cm³
Appearance
Off-white solid
Application
Poly(2-ethyl-2-oxazoline) serves as a versatile and innovative polymer due to its unique properties and applications. This amorphous, water-soluble polymer is known for its excellent temperature stability and biocompatibility. Research led by Jordan and team has demonstrated that it does not accumulate in tissues and is rapidly cleared from the bloodstream, making it a suitable candidate for medical applications. It is increasingly gaining attention as a potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone) due to its end-group modification capability, which allows for effective conjugation with peptides and serves as a viable alternative to poly(ethylene glycol) for the conjugation of proteins and small drugs. Additionally, Poly(2-ethyl-2-oxazoline) is utilized as an adhesion promoter in coatings and is highly effective as a heat sealing agent and remoistenable hot-melt adhesive. Its compatibility with solvents such as acetone, DMF, ethanol, MEK, methanol, methylene chloride, THF, and water further enhances its utility across various industrial and pharmaceutical applications.
Assay
0.99
Complexity
88.1
Covalently-Bonded Unit Count
1
EC Number
233-912-4
Exact Mass
99.068414g/mol
Formal Charge
0
Heavy Atom Count
7
MDL Number
MFCD00134377
MeSH Entry Terms
2-ethyl-2-oxazoline
Monoisotopic Mass
99.068414g/mol
NSC Number
136557
Packaging
100 g
Refractive Index
n20/D 1.52
Rotatable Bond Count
1
UNII
B8CD92T4P5
XLogP3
0.3
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