Medical grade beta tricalcium phosphate (β-TCP) is a bioceramic material widely recognized for its outstanding biocompatibility, osteoconductivity, and resorbability. As a synthetic calcium phosphate compound, β-TCP closely resembles the mineral component of human bone, making it an excellent choice for bone repair, regeneration, and tissue engineering applications. Over the past decades, β-TCP has become one of the most commonly used materials in orthopedic, dental, and maxillofacial surgeries, either as a standalone bone graft substitute or as a component of composite scaffolds.
Chemical and Structural Characteristics
Beta tricalcium phosphate has the chemical formula Ca3(PO4)2 and exists as one of two crystalline forms of tricalcium phosphate, the other being alpha-TCP. Compared with the alpha phase, β-TCP is thermodynamically stable at lower temperatures and exhibits a slower dissolution rate in physiological environments, which makes it ideal for controlled bone resorption. Its crystal structure provides a balance between mechanical stability and biological activity, allowing gradual replacement by new bone during the healing process. Furthermore, β-TCP powders and granules can be sintered into porous scaffolds, whose pore size and interconnectivity significantly influence cellular infiltration and nutrient transport.
Biological Properties
The biological performance of medical grade β-TCP stems from its ability to interact with bone cells and body fluids. When implanted, β-TCP undergoes partial dissolution, releasing calcium and phosphate ions that stimulate osteoblast proliferation and promote mineralization. Its osteoconductive property enables bone growth along its surface and within its pores, providing a structural framework for new tissue formation. Additionally, β-TCP is fully resorbable, meaning it can be gradually replaced by natural bone without leaving any toxic residues. This balance between degradation and new bone formation is crucial for successful integration with host tissues.
Applications in Medicine
Medical grade β-TCP is extensively used across various medical disciplines due to its biocompatibility, osteoconductivity, and resorbability. Its major applications include:
β-TCP is employed as a bone graft substitute to repair bone defects, promote spinal fusion, and fill voids after trauma or tumor removal. It supports new bone formation while gradually resorbing, eliminating the need for secondary removal procedures.
- Dental and Maxillofacial Surgery
In dentistry, β-TCP is used for socket preservation, sinus lift, and ridge augmentation procedures. It enhances bone regeneration around implants and improves osseointegration, contributing to long-term implant stability.
β-TCP serves as a scaffold material that can be combined with biopolymers, stem cells, or growth factors to create three-dimensional structures for bone and cartilage regeneration. Its porous architecture facilitates cell migration, vascularization, and nutrient exchange.
Our Products
We offer a range of medical grade β-TCP. The specific parameters of these products are as follows:
| Catalog Number | Matrix | Average Particle Size | Morphology | Appearance | Purity | Pore Size |
| ALCM-BM-01 | β-TCP | 200 nm | Amorphous | White Powder | >98% | / |
| ALCM-BM-02 | β-TCP | 5-200 um | Amorphous | White Powder | >98% | / |
| ALCM-BM-03 | β-TCP | 10-200 um | Spherical | White Powder | >98% | <20 um |
| ALCM-BM-04 | β-TCP | 0.2-0.5 mm | / | Granules | >98% | 100-500 um |
| ALCM-BM-05 | β-TCP | 0.5-1 mm | / | Granules | >98% | 100-500 um |
| ALCM-BM-06 | β-TCP | 1-2 mm | / | Granules | >98% | 100-500 um |
| ALCM-BM-07 | β-TCP | 2-3 mm | / | Granules | >98% | 100-500 um |
| ALCM-BM-08 | β-TCP | 3-5 mm | / | Granules | >98% | 100-500 um |
Medical grade β-TCP represents a vital class of biomaterials for modern regenerative medicine. Its unique combination of biocompatibility, resorbability, and osteoconductivity makes it indispensable in bone tissue engineering and surgical repair. If you are interested in such products, please contact us immediately.
