CAS 25086-89-9 Poly(1-vinylpyrrolidone-co-vinyl acetate)

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Poly(1-vinylpyrrolidone-co-vinyl acetate)

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Catalog Number

ACM25086899-7

CAS Number

25086-89-9

Product Name

Poly(1-vinylpyrrolidone-co-vinyl acetate)

Structure

Category

Hydrophilic Polymers; Hydrophobic Polymers; Polymers

IUPAC Name

ethenyl acetate;1-ethenylpyrrolidin-2-one

Molecular Weight

197.23g/mol

Molecular Formula

C10H15NO3

Canonical SMILES

CC(=O)OC=C.C=CN1CCCC1=O

InChI

InChI=1S/C6H9NO.C4H6O2/c1-2-7-5-3-4-6(7)8;1-3-6-4(2)5/h2H,1,3-5H2;3H,1H2,2H3

InChI Key

FYUWIEKAVLOHSE-UHFFFAOYSA-N

Density

1.27

Appearance

White powder

Application

Poly(1-vinylpyrrolidone-co-vinyl acetate) serves as a versatile, water-soluble polymer widely utilized in the pharmaceutical industry to enhance the uptake and drug loading of various medications, including those used in contraceptive patches. This polymer, typically an amorphous powder with a slight odor and taste, functions effectively as a tablet binder and film-former. In tablet production, it serves as a binder for both direct compression and wet granulation processes. Additionally, it is frequently incorporated into coating solutions as a film-forming agent, providing excellent adhesion, elasticity, and hardness, while also acting as an effective moisture barrier in controlled-release formulations.

Assay

0.99

Complexity

186

Covalently-Bonded Unit Count

EC Number

607-540-1

Exact Mass

197.105193g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

copovidone;Kollidon VA64;poly(V-co-V-Ac);poly(vinyl pyrrolidone-co-vinyl acetate);poly(vinylpyrrolidone-co-vinyl-acetate);polyvidone-vinylacetate 64;PVP VA64;PVP-VA;PVPVA 64

Monoisotopic Mass

197.105193g/mol

NSC Number

114026;114025;114024;114023

Packaging

1 kg

Rotatable Bond Count

Stability

Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.

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