CAS 81290-20-2 Trimethyl(trifluoromethyl)silane solution

NAVIGATION

Trimethyl(trifluoromethyl)silane solution

PRICE INQUIRY

Catalog Number

ACM81290202-1

CAS Number

81290-20-2

Product Name

Trimethyl(trifluoromethyl)silane solution

Structure

Category

Salt

IUPAC Name

trimethyl(trifluoromethyl)silane

Molecular Weight

142.19g/mol

Molecular Formula

C4H9F3Si

Canonical SMILES

C[Si](C)(C)C(F)(F)F

InChI

InChI=1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3

InChI Key

MWKJTNBSKNUMFN-UHFFFAOYSA-N

Application

Trimethyl(trifluoromethyl)silane solution serves as a key trifluoromethylation reagent in the field of synthetic organic chemistry, specifically used in nucleophilic addition reactions with aldehydes and ketones to facilitate the formation of carbon-carbon bonds. This colorless, flammable liquid is advantageous for its ability to efficiently introduce trifluoromethyl groups into various substrates, including carbonyls and ethylene diamines, as well as aromatic, heteroaromatic, and vinyl compounds through metal-mediated processes. Although effective, it requires careful handling due to its potential harm if inhaled, ingested, or absorbed through the skin, and it can cause irritation to the respiratory tract, skin, and eyes.

Complexity

78.3

Covalently-Bonded Unit Count

Exact Mass

142.042561g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

(trifluoromethyl)-trimethylsilane;(trifluoromethyl)trimethylsilane;CF3SiMe3

Monoisotopic Mass

142.042561g/mol

Rotatable Bond Count