CAS 81290-20-2 Trimethyl(trifluoromethyl)silane

NAVIGATION

Trimethyl(trifluoromethyl)silane

PRICE INQUIRY

Catalog Number

ACM81290202

CAS Number

81290-20-2

Product Name

Trimethyl(trifluoromethyl)silane

Category

Salt

IUPAC Name

trimethyl(trifluoromethyl)silane

Molecular Weight

142.19g/mol

Molecular Formula

C4H9F3Si

Canonical SMILES

C[Si](C)(C)C(F)(F)F

InChI

InChI=1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3

InChI Key

MWKJTNBSKNUMFN-UHFFFAOYSA-N

Application

Trimethyl(trifluoromethyl)silane is a versatile trifluoromethylation reagent primarily used in nucleophilic addition reactions involving aldehydes and ketones, enabling C-C bond formation. This flammable, colorless liquid, boasting a boiling point of 54-55 °C, is instrumental in the silicon-based trifluoromethylation of various substrates, including carbonyls and ethylene diamines, and acts as a precursor for metal-mediated transformations of aromatic, heteroaromatic, and vinyl compounds. While its chemical properties enhance its utility in organic synthesis, appropriate precautions should be taken due to its potential harmful effects through inhalation, ingestion, or skin absorption, as well as its ability to irritate the respiratory tract, skin, and eyes.

Complexity

78.3

Covalently-Bonded Unit Count

Exact Mass

142.042561g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

(trifluoromethyl)-trimethylsilane;(trifluoromethyl)trimethylsilane;CF3SiMe3

Monoisotopic Mass

142.042561g/mol

Rotatable Bond Count