NAVIGATION


SLAP HydroPyridopyrazine Reagent

Catalog NumberACM2023645227

CAS Number2023645-22-7

CategorySalt

Application
The SLAP HydroPyridopyrazine Reagent serves the purpose of enabling the efficient synthesis of N-unprotected piperazines through a photocatalytic cross-coupling method. This process utilizes aldehydes and ketones in combination with the SLAP HydroPyridopyrazine Reagent and the catalyst Ir[(ppy)2dtbbpy]PF6. It accommodates a wide range of substrate types, including heteroaromatic, aromatic, and aliphatic aldehydes, as well as complex SLAP reagents, ensuring versatility and robustness in chemical synthesis. Developed in collaboration with the Bode Research Group, this reagent offers a tin-free alternative to SnAP reagents, enhancing the synthesis process for piperazines without the need for tin-based components.
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