Poly(2-ethyl-2-oxazoline) - Materials / Alfa Chemistry

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Biomaterials

Hydrophilic Polymers

Poly(2-ethyl-2-oxazoline)

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Catalog Number

ACMA00003293

Product Name

Poly(2-ethyl-2-oxazoline)

Structure

Category

Hydrophilic Polymers

Synonyms

Me-PEtOx-OH

Description

2-Ethyl-2-oxazoline is an oxazoline which is used particularly as a monomer for the cationic ring-opening polymerization to poly(2-alkyloxazoline)s. This type of polymers are under investigation as readily water-soluble and biocompatible materials for biomedical applications.

IUPAC Name

2-ethyl-4,5-dihydro-1,3-oxazole

Molecular Weight

average Mn 5,000

Molecular Formula

CH3(C5H9NO)nOH

Canonical SMILES

CCC1=NCCO1

InChI

InChI=1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI Key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

Application

The polymerization of 2-ethyl-2-oxazoline can also be carried out as a living cationic polymerization.
Copolymers with other 2-alkyl-2-oxazolines and other monomers can prepare random and block copolymers.
The obtained copolymers can be used as biocompatible drug carriers for coatings and adhesives, among many other applications.
Elimination of propionyl groups from poly(2-ethyl-2-oxazoline) yields linear polyethyleneimine.

Complexity

88.1

Covalently-Bonded Unit Count

EC Number

233-912-4

Exact Mass

99.068414g/mol

Features And Benefits

2-Ethyl-2-oxazoline is a colorless liquid that is easily soluble in water, also soluble in various organic solvents, and has an amine odor. The aqueous solution is alkaline. The compound is stable in alkali, but hydrolyzes under the action of acid.

Formal Charge

Heavy Atom Count

MeSH Entry Terms

2-ethyl-2-oxazoline

Monoisotopic Mass

99.068414g/mol

NSC Number

136557

Rotatable Bond Count

Storage Temperature

2-8°C

UNII