CAS 9045-22-1 Heparin lithium salt from porcine intestinal mucosa

NAVIGATION

Heparin lithium salt from porcine intestinal mucosa

PRICE INQUIRY

Catalog Number

ACM9045221

CAS Number

9045-22-1

Product Name

Heparin lithium salt from porcine intestinal mucosa

Category

Polysaccharide

IUPAC Name

(2R,3S,4S,5R,6R)-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3-methoxy-5-sulfooxyoxane-2-carboxylic acid

Molecular Weight

623.5g/mol

Molecular Formula

C14H25NO20S3

Canonical SMILES

COC1C(C(C(OC1C(=O)O)OC2C(OC(C(C2O)NS(=O)(=O)O)OC)COS(=O)(=O)O)OS(=O)(=O)O)O

InChI

InChI=1S/C14H25NO20S3/c1-29-9-7(17)10(35-38(26,27)28)14(34-11(9)12(18)19)33-8-4(3-31-37(23,24)25)32-13(30-2)5(6(8)16)15-36(20,21)22/h4-11,13-17H,3H2,1-2H3,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28)/t4-,5-,6-,7+,8-,9+,10-,11-,13+,14-/m1/s1

InChI Key

HXSDFQWQRCUQHF-IDOMHHBZSA-N

Application

Heparin lithium salt from porcine intestinal mucosa is a white to off-white powder created by replacing sodium ions with lithium ions. This product serves as an anticoagulant, playing a crucial role in the medical field. As a glycosaminoglycan, it is biosynthesized and stored in the mast cells of various mammalian tissues, including the liver, lung, and mucosa. Commercially, it is primarily derived from pork intestinal mucosa. The key function of heparin lithium salt is to bind with antithrombin III, a natural plasma protease inhibitor, which significantly enhances the inhibition of coagulation proteases such as Factor Xa and thrombin.

Complexity

1120

Covalently-Bonded Unit Count

Exact Mass

623.013206g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

623.013206g/mol

Rotatable Bond Count

XLogP3

-5.4