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2-Hydroxyethyl cellulose

Catalog Number
ACM9004620-5
CAS Number
9004-62-0
Product Name
2-Hydroxyethyl cellulose
Category
Natural Polymers and Biopolymers
Description
WHITE POWDER.
IUPAC Name
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
Molecular Weight
736.7g/mol
Molecular Formula
(C2H602)x;C29H52O21
Canonical SMILES
CC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)OC)O)O)OC4C(C(C(C(O4)CO)OC)O)OCCO)O)O)O)O
InChI
InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3
InChI Key
CWSZBVAUYPTXTG-UHFFFAOYSA-N
Solubility
Solubility in water: good
Application
2-Hydroxyethyl cellulose is a versatile, nonionic, water-soluble polymer that serves multiple functions in various applications. Primarily, it acts as a thickening agent in pharmaceutical formulations, particularly in ophthalmic and topical preparations. Additionally, it is used as a binder and film-coating agent for tablets, enhancing the structural integrity and appearance of the product. In the field of personal care, it plays a vital role in products designed for dry eyes, contact lens care, and dry mouth due to its lubricating properties. The effectiveness of 2-hydroxyethyl cellulose in any formulation depends on the solvent used and the molecular weight of its particular grade. Furthermore, it finds widespread application in the cosmetics industry, benefiting from its ability to enhance texture and stability in a variety of skincare and beauty products.
Complexity
999
Covalently-Bonded Unit Count
1
EC Number
618-387-5
Exact Mass
736.300109g/mol
Formal Charge
0
Heavy Atom Count
50
ICSC Number
1559
MeSH Entry Terms
aldiamed;hydroxyethylcellulose;hydroxyethylcellulose, sodium salt;hydroxyl ethyl cellulose;Lacrigel;Minims Artificial Tears;Natrosol 250
Monoisotopic Mass
736.300109g/mol
Rotatable Bond Count
15
RTECS Number
FJ5958000
XLogP3
-7.7
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