CAS 77-89-4 Triethyl O-Acetylcitrate - Materials / Alfa Chemistry

NAVIGATION

Triethyl O-Acetylcitrate

PRICE INQUIRY

Catalog Number

ACM77894-1

CAS Number

77-89-4

Product Name

Triethyl O-Acetylcitrate

Category

Plastic Additives; Plasticizers

Synonyms

triethyl 2-acetyloxypropane-1,2,3-tricarboxylate;1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester;

Description

Triethyl O-Acetylcitrate is used in the preparation of poly(lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings.

IUPAC Name

triethyl 2-acetyloxypropane-1,2,3-tricarboxylate

Molecular Weight

318.32g/mol

Molecular Formula

C14H22O8

Canonical SMILES

CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)OC(=O)C

InChI

InChI=1S/C14H22O8/c1-5-19-11(16)8-14(22-10(4)15,13(18)21-7-3)9-12(17)20-6-2/h5-9H2,1-4H3

InChI Key

WEAPVABOECTMGR-UHFFFAOYSA-N

Melting Point

-42ºC

Flash Point

>110ºC

Density

1.137

Appearance

Colorless or light yellow liquid

Application

Triethyl O-Acetylcitrate serves as a versatile plasticizer primarily used in the production of biodegradable and flexible films made from poly(lactic) acid. Its role extends to aiding in the synthesis of controlled-release capsules with polymeric coatings and applications in aqueous-based pharmaceutical coatings. This compound is instrumental in formulating pharmaceutical coatings for capsules, tablets, beads, and granules, providing benefits such as taste masking, immediate release, sustained-release, and enteric formulations. Additionally, it plays a key role in diffusion-controlled release drug delivery systems, enhancing the overall efficacy and functionality of these pharmaceutical applications.

Complexity

395

Covalently-Bonded Unit Count

EC Number

201-066-5

Exact Mass

318.131468g/mol

Formal Charge

Heavy Atom Count

Log P

0.75780

MeSH Entry Terms