SLAP 3-SpiroCyHex N-Bn Pip Reagent - Materials / Alfa Chemistry

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SLAP 3-SpiroCyHex N-Bn Pip Reagent

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Catalog Number

ACMA00015534

Product Name

SLAP 3-SpiroCyHex N-Bn Pip Reagent

Category

Salt

Application

The SLAP 3-SpiroCyHex N-Bn Pip Reagent serves as an advanced tool for synthesizing N-unprotected piperazines through a photocatalytic cross-coupling process with aldehydes and ketones, using Ir[(ppy)2dtbbpy]PF6 as a catalyst. It efficiently accommodates a variety of aldehydes-heteroaromatic, aromatic, and aliphatic-as well as SLAP reagents that possess complex structural and stereochemical features. Developed in collaboration with the Bode Research Group, this reagent offers a tin-free alternative to traditional SnAP reagents, enhancing the versatility and safety of piperazine synthesis.

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