SLAP 2,3-Bicyclo-(3,4-THF) N-BnPip Reagent - Materials / Alfa Chemistry

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SLAP 2,3-Bicyclo-(3,4-THF) N-BnPip Reagent

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Catalog Number

ACMA00015553

Product Name

SLAP 2,3-Bicyclo-(3,4-THF) N-BnPip Reagent

Category

Salt

Application

The SLAP 2,3-Bicyclo-(3,4-THF) N-BnPip Reagent is designed to facilitate the formation of N-unprotected piperazines through photocatalytic cross-coupling when used with aldehydes and ketones, utilizing the Ir[(ppy)2dtbbpy]PF6 catalyst. This reagent is compatible with a wide range of substrates, including heteroaromatic, aromatic, and aliphatic aldehydes, as well as complex structural and stereochemical SLAP reagents. Developed in collaboration with the Bode Research Group, this product offers a tin-free alternative to traditional SnAP (tin amine protocol) reagents for efficient piperazine synthesis.

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