Catalog Number
ACMA00003225
Product Name
Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)
Category
Biodegradable Polymers; Poly(ethylene glycol) and Poly(ethylene oxide)
Synonyms
mPEG-PLLA, Biodegradable, PLLA, PEG-PLA, Drug delivery, mPEG-PLA, Block copolymer
Description
Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block.
Molecular Weight
PDLA average Mn 20,000 (by NMR)
PDLLA average Mn 20000
PEG average Mn 5,000 (by NMR)
PEG average Mn 5000
Molecular Formula
HO[CH(CH3)COO]m[CH2CH2O]nCH3
Application
Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).
Features And Benefits
These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media.
Packaging
1 g in glass bottle