CAS 9003-11-6 Poloxamer 188 solution - Materials / Alfa Chemistry

NAVIGATION

Poloxamer 188 solution

PRICE INQUIRY

Catalog Number

ACM9003116-4

CAS Number

9003-11-6

Product Name

Poloxamer 188 solution

Category

Poly(ethylene glycol) and Poly(ethylene oxide)

Description

Liquid

IUPAC Name

2-methyloxirane;oxirane

Molecular Weight

102.13g/mol

Molecular Formula

C5H10O2

Canonical SMILES

CC1CO1.C1CO1

InChI

InChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI Key

RVGRUAULSDPKGF-UHFFFAOYSA-N

Application

Poloxamer 188 solution serves a multifaceted purpose in pharmaceutical and therapeutic applications due to its unique properties as a nonionic polyoxyethylene-polyoxypropylene copolymer. Primarily, it is employed as an emulsifying and solubilizing agent, which is crucial in maintaining the clarity and stability of pharmaceutical formulations such as intravenous fat emulsions, elixirs, and syrups. Its versatility extends to functioning as a wetting agent in diverse medical applications, including oral administration as a stool lubricant to aid in constipation treatment, often in combination with a laxative. Furthermore, it plays a significant role in drug-delivery systems and can be found in formulations for eye drops, serving as a therapeutic agent in the treatment of kidney stones and as a skin-wound cleanser. This solution's ability to act as an emulsifying agent also supports the preparation of solid-dispersion systems and the development of artificial blood substitutes.

Color/Form

Liquid

Complexity

36.7

Covalently-Bonded Unit Count

EC Number

618-355-0;923-642-1

Exact Mass

102.06808g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass