O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol

Name: O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol
SKU: ACM857891828
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Catalog NumberACM857891828

CAS Number857891-82-8

CategoryPoly(ethylene glycol) and Poly(ethylene oxide); Polymers

O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol

IUPAC Name

2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine

Molecular Weight

438.5g/mol

Molecular Formula

C18H38N4O8

Canonical SMILES

C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N

InChI

InChI=1S/C18H38N4O8/c19-1-3-23-5-7-25-9-11-27-13-15-29-17-18-30-16-14-28-12-10-26-8-6-24-4-2-21-22-20/h1-19H2

InChI Key

ZSFGTBJYBWJOLZ-UHFFFAOYSA-N

Application

O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol is utilized for enhancing the surface properties of bicompartmental poly(lactide-co-glycolide) (PLGA) fibers and particles. It achieves this through surface-selective click chemistry, allowing for the creation of spatioselectively modified particles and fibers. This modification process plays a crucial role in a range of biomedical applications. The compound features an azide group and a free amine group, making it an aqueous soluble heterobifunctional reagent. The azide group facilitates click chemistry reactions, while the amine group reacts effectively with carboxylic acids and activated NHS esters, further broadening its utility in biomedical research and development.

Complexity

376

Covalently-Bonded Unit Count

Exact Mass

438.268964g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

438.268964g/mol

Rotatable Bond Count

XLogP3

-1