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  • O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol

  • O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol

    Catalog Number
    ACM857891828
    CAS Number
    857891-82-8
    Product Name
    O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol
    Structure
    Category
    Poly(ethylene glycol) and Poly(ethylene oxide); Polymers
    IUPAC Name
    2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
    Molecular Weight
    438.5g/mol
    Molecular Formula
    C18H38N4O8
    Canonical SMILES
    C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N
    InChI
    InChI=1S/C18H38N4O8/c19-1-3-23-5-7-25-9-11-27-13-15-29-17-18-30-16-14-28-12-10-26-8-6-24-4-2-21-22-20/h1-19H2
    InChI Key
    ZSFGTBJYBWJOLZ-UHFFFAOYSA-N
    Application
    O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol is utilized for enhancing the surface properties of bicompartmental poly(lactide-co-glycolide) (PLGA) fibers and particles. It achieves this through surface-selective click chemistry, allowing for the creation of spatioselectively modified particles and fibers. This modification process plays a crucial role in a range of biomedical applications. The compound features an azide group and a free amine group, making it an aqueous soluble heterobifunctional reagent. The azide group facilitates click chemistry reactions, while the amine group reacts effectively with carboxylic acids and activated NHS esters, further broadening its utility in biomedical research and development.
    Complexity
    376
    Covalently-Bonded Unit Count
    1
    Exact Mass
    438.268964g/mol
    Formal Charge
    0
    Heavy Atom Count
    30
    Monoisotopic Mass
    438.268964g/mol
    Rotatable Bond Count
    26
    XLogP3
    -1
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