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  • N-Succinimidyl 3-Maleimidobenzoate, ≥98%

  • N-Succinimidyl 3-Maleimidobenzoate, ≥98%

    Catalog Number
    ACM58626383-1
    CAS Number
    58626-38-3
    Product Name
    N-Succinimidyl 3-Maleimidobenzoate, ≥98%
    Category
    Crosslinkers
    IUPAC Name
    (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)benzoate
    Molecular Weight
    314.25g/mol
    Molecular Formula
    C15H10N2O6
    Canonical SMILES
    C1CC(=O)N(C1=O)OC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O
    InChI
    InChI=1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
    InChI Key
    LLXVXPPXELIDGQ-UHFFFAOYSA-N
    Application
    N-Succinimidyl 3-Maleimidobenzoate, ≥98%, is designed for applications in forming enzyme immunoconjugates. This heterobifunctional crosslinking reagent features a 9.9-angstrom spacer arm and is uniquely reactive towards primary amines and sulfhydryls, making it highly effective for preparing both enzyme immunoconjugates and hapten carrier molecule conjugates. The maleimide group in its structure specifically targets sulfhydryl groups, while the NHS ester efficiently reacts with amine groups, facilitating precise and versatile crosslinking opportunities.
    Complexity
    592
    Covalently-Bonded Unit Count
    1
    EC Number
    261-368-8
    Exact Mass
    314.053886g/mol
    Formal Charge
    0
    Heavy Atom Count
    23
    MeSH Entry Terms
    3-maleimidobenzoyl N-hydroxysuccinimide;3-maleimidobenzoyl N-hydroxysuccinimide ester;m-maleimidobenzoic acid N-hydroxysuccinimide ester;meta-maleimidobenzoyl N-hydroxysuccinimide;N-(m-maleimidobenzoyloxy)succinimide;N-succinimidyl m-maleimidobenzoate
    Monoisotopic Mass
    314.053886g/mol
    NSC Number
    294786
    Rotatable Bond Count
    4
    XLogP3
    0
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