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  • Hydroxyethyl Cellulose (4500-6500mPa·s, 2% in Water at 25°C)

    Catalog Number
    ACM9004620-15
    CAS Number
    9004-62-0
    Product Name
    Hydroxyethyl Cellulose (4500-6500mPa·s, 2% in Water at 25°C)
    Category
    Polymers
    Description
    WHITE POWDER.
    IUPAC Name
    5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
    Molecular Weight
    736.7g/mol
    Molecular Formula
    (C2H602)x;C29H52O21
    Canonical SMILES
    CC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)OC)O)O)OC4C(C(C(C(O4)CO)OC)O)OCCO)O)O)O)O
    InChI
    InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3
    InChI Key
    CWSZBVAUYPTXTG-UHFFFAOYSA-N
    Solubility
    Solubility in water: good
    Application
    Hydroxyethyl Cellulose (4500-6500mPa·s, 2% in Water at 25°C) is a versatile, nonionic, water-soluble polymer primarily utilized for its thickening and stabilizing properties. Appearing as a white to grayish-white, odorless and tasteless, hygroscopic powder, it serves a crucial role in various formulations. In the pharmaceutical industry, it is widely employed as a thickening agent in ophthalmic and topical products, as well as a binder and film-coating agent for tablets. Its utility extends to cosmetics, where it enhances product texture and stability. Derived from wood pulp or chemical cotton through alkali treatment, Hydroxyethyl Cellulose's functionality in formulations is influenced by its molecular weight and the solvent used. It is a key component in lubricant preparations for addressing dry eye conditions, contact lens care, and dry mouth, offering reliable performance across diverse applications.
    Complexity
    999
    Covalently-Bonded Unit Count
    1
    EC Number
    618-387-5
    Exact Mass
    736.300109g/mol
    Formal Charge
    0
    Heavy Atom Count
    50
    ICSC Number
    1559
    MeSH Entry Terms
    aldiamed;hydroxyethylcellulose;hydroxyethylcellulose, sodium salt;hydroxyl ethyl cellulose;Lacrigel;Minims Artificial Tears;Natrosol 250
    Monoisotopic Mass
    736.300109g/mol
    Rotatable Bond Count
    15
    RTECS Number
    FJ5958000
    XLogP3
    -7.7
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