CAS 1837-91-8 1,2,3,4,5,6-Hexabromocyclohexane

NAVIGATION

1,2,3,4,5,6-Hexabromocyclohexane

PRICE INQUIRY

Catalog Number

ACM1837918-1

CAS Number

1837-91-8

Product Name

1,2,3,4,5,6-Hexabromocyclohexane

Category

Plastic Additives

IUPAC Name

1,2,3,4,5,6-hexabromocyclohexane

Molecular Weight

557.5g/mol

Molecular Formula

C6H6Br6

Canonical SMILES

C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br

InChI

InChI=1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H

InChI Key

QFQZKISCBJKVHI-UHFFFAOYSA-N

Purity

>97%

Application

The primary purpose of 1,2,3,4,5,6-Hexabromocyclohexane is to serve as a potent and specific inhibitor of JAK2 autophosphorylation, which is a key process involving JAK2 tyrosine kinase activity. This compound functions as a non-specific protein-tyrosine kinase inhibitor, effectively impeding the enzyme's autophosphorylation. Structurally, it is a bromohydrocarbon derived from cyclohexane, with all hydrogen atoms replaced by bromo groups, and plays a crucial role in regulating kinase activity through its inhibitory effects.

Complexity

104

Covalently-Bonded Unit Count

Exact Mass

557.55083g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

1,2,3,4,5,6-hexabromocyclohexane

Monoisotopic Mass

551.55698g/mol

NSC Number