CAS 7751-38-4 Diisopropyldichlorosilane - Materials / Alfa Chemistry

NAVIGATION

Diisopropyldichlorosilane

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Catalog Number

ACM7751384-4

CAS Number

7751-38-4

Product Name

Diisopropyldichlorosilane

Category

Polymers

Synonyms

Dichlorodiisopropylsilanedichloro[Bis(1-Methylethyl)]Silane

IUPAC Name

dichloro-di(propan-2-yl)silane

Molecular Weight

185.17 g/mol

Molecular Formula

C6H14Cl2Si

Canonical SMILES

CC(C)[Si](C(C)C)(Cl)Cl

InChI Key

GSENNYNYEKCQGA-UHFFFAOYSA-N

Boiling Point

66 °C(27 mmHg,lit.)

Melting Point

<0 °C

Flash Point

43 °C

Purity

0.97

Density

1.026 g/mL (20 °C,lit.)

Appearance

Transparent liquid

Application

Diisopropyldichlorosilane serves as a valuable reagent for protecting the 3' and 5' hydroxy groups in nucleosides. By employing the diisopropylsilyl group, this compound acts as a bifunctional protecting group, facilitating the shielding of hydroxy groups during chemical reactions. When reacted with nucleosides in the presence of imidazole and DMF, diisopropyldichlorosilane efficiently forms a protected nucleoside, making it a useful yet underutilized method compared to the more commonly used tetraisopropyldisiloxy group for 3',5'-hydroxy protection.

Exact Mass

184.02400

Hazard Statements

Packaging

10 g; 100 g;

Safety Description

S28-S45-S36-S37-S39

WGK Germany

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