Dextran sulfate sodium salt - Materials / Alfa Chemistry

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Dextran sulfate sodium salt

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Catalog Number

ACMA00003340

Product Name

Dextran sulfate sodium salt

Category

Natural Polymers and Biopolymers

Application

Dextran sulfate sodium salt is primarily utilized for its versatile role in various experimental and therapeutic applications. This white to off-white powder, derived from Leuconostoc species, is commonly used as a standard in carbohydrate polyacrylamide-gel electrophoresis (C-PAGE) and RNA sequential probing of targets (SPOTs) imaging, making it indispensable in molecular biology research. Additionally, it serves as a component in injection buffers. Beyond these applications, dextran sulfate has attracted attention for its role in anticoagulant research as a potential alternative to heparin, particularly its low molecular weight forms that display notable, albeit limited, anticoagulant properties. Its capabilities extend to medical treatments, such as selectively removing LDL cholesterol during plasmapheresis. Its broad biological activities, including enzyme modulation, enhancement of immune responses, cellular interactions, and effects on viral infectivity, make dextran sulfate a substance of significant interest in scientific research.

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