CAS 3458-28-4 D-Mannose - Materials / Alfa Chemistry

NAVIGATION

D-Mannose

PRICE INQUIRY

Catalog Number

ACM3458284

CAS Number

3458-28-4

Product Name

D-Mannose

Structure

Category

Polymers

Synonyms

(+)-Mannose,Carubinose,D(+)-Mannose,Mannose,Seminose

Molecular Weight

180.16

Molecular Formula

C6H12O6

Boiling Point

232.96 °C

Melting Point

133-140 °C (lit.)

Purity

98%

Density

1.539 g/cm³

Solubility

Soluble in water

Appearance

White powder

Application

D-Mannose, a white crystalline powder, serves a vital role in glycosylation processes within human metabolism and cellular functions. This carbohydrate, structurally akin to glucose, is responsible for the N and O glycosylation of proteins, including those used in infant formulas and the T helper cell-derived cytokine interleukin-17A, which is crucial for cell signaling. Found naturally in fruits such as cranberries and peaches, D-mannose is particularly effective in preventing urinary tract infections (UTIs) by binding to the lectins on E. coli bacteria's fimbria, thereby facilitating their expulsion via urination. Additionally, D-mannose is used in treating carbohydrate-deficient glycoprotein syndrome and serves as a reference standard in monosaccharide analysis. Its slow absorption in the gastrointestinal tract and substantial excretion in the urine make it the most effective supplement for UTI prevention and treatment. Furthermore, D-mannose is utilized in selecting transfected sorghum seeds and as a culture medium supplement for human cell lines, underscoring its multifaceted applications in both health and research contexts.

Storage Conditions

Room Temperature

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