Catalog Number
ACM299285-1
Product Name
Calcium Gluconate
Synonyms
D-Gluconic acid, calcium salt
Description
Calcium gluconate is a mineral supplement. It is manufactured by the neutralization of gluconic acid with lime or calcium carbonate.It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
IUPAC Name
Calcium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
Molecular Formula
C12H22CaO14
Canonical SMILES
C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Ca+2]
InChI
InChI=1S/2C6H12O7.Ca/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
InChI Key
NEEHYRZPVYRGPP-IYEMJOQQSA-L
Solubility
Soluble in water, insoluble in ethanol;Slowly soluble in 5 parts boiling water; insoluble in alc or other organic solvents. Slowly soluble in 30 parts cold, about 5 parts boiling water;Insoluble in acetic acid;Sol in water 3.3 g/100 cc at 15 °C;In water, 3.33X10+4 mg/L at 25 °C;Solubility in water, g/100ml at 25 °C: 3.5 (moderate)
Application
Calcium gluconate serves multiple purposes, primarily functioning as a mineral supplement and medication. As a calcium salt of D-gluconic acid, it is often utilized when dietary calcium is insufficient, thereby supporting bone health and addressing deficiencies. In medical settings, it is utilized intravenously to correct low blood calcium levels, combat high blood potassium, and counteract magnesium toxicity, with careful monitoring of plasma calcium levels and electrocardiographic changes. Additionally, calcium gluconate is effective for easing muscle cramps resulting from black widow spider bites and is employed in the management of osteoporosis and rickets. Beyond medicinal uses, it fortifies foods and beverages that are low in calcium and acts as an inert ingredient in pesticide formulations. Its versatility extends to reducing capillary permeability in allergic reactions and various skin conditions, making it a valuable component in both health and agricultural sectors.
Color/Form
Crystals, granules, or powder
Covalently-Bonded Unit Count
3
EC Number
206-075-8;206-075-8;605-881-0
Exact Mass
430.063546g/mol
MeSH Entry Terms
Calciofon;Calcipot;Calcium Braun;Calcium Gluconate;Calcivitol;Calglucon;CBG;Ebucin;Flopak Plain;Glucal;Glucobiogen;Gluconate de Calcium Lavoisier;Gluconate, Calcium;Gluconato Calc Fresenius
Monoisotopic Mass
430.063546g/mol
Other Experimental
Soln is neutral to litmus paper;Does not lose its water on drying without some decomp;Stable in air. Loses water at 120 °C.;Calcium gluconate is decomposed by dilute mineral acids into gluconic acid and the calcium salt of the mineral acid used. It is precipitated from its aqueous solution by the addition of alcohol.
Stability
Stable. Incompatible with strong oxidizing agents.
Storage Conditions
Store in a cool, dry place. Keep container closed when not in use.