NAVIGATION


Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution

Catalog NumberACMA00015577

CategorySalt

Application
The Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution is designed to serve as a versatile base in zincation reactions. Its primary purpose is to facilitate regioselective zincation of pyridines and related azines, enabling the synthesis of zincated pyridines and azines. Additionally, it supports the chemoselective direct zincation of arenes and heteroarenes, allowing for the creation of polyfunctional aryl and heteroaryl zinc reagents. The complex solution is also effective in the regioselective zincation of thiazoles, which can then be reacted with various electrophiles to form highly functionalized thiazoles.
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