CAS 873013-93-5 acid-PEG8-S-S-PEG8-acid - Materials / Alfa Chemistry

NAVIGATION

acid-PEG8-S-S-PEG8-acid

PRICE INQUIRY

Catalog Number

ACM873013935-2

CAS Number

873013-93-5

Product Name

acid-PEG8-S-S-PEG8-acid

Structure

Category

Poly(ethylene glycol) and Poly(ethylene oxide)

IUPAC Name

3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyldisulfanyl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Molecular Weight

915.1g/mol

Molecular Formula

C38H74O20S2

Canonical SMILES

C(COCCOCCOCCOCCOCCOCCOCCOCCSSCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O

InChI

InChI=1S/C38H74O20S2/c39-37(40)1-3-43-5-7-45-9-11-47-13-15-49-17-19-51-21-23-53-25-27-55-29-31-57-33-35-59-60-36-34-58-32-30-56-28-26-54-24-22-52-20-18-50-16-14-48-12-10-46-8-6-44-4-2-38(41)42/h1-36H2,(H,39,40)(H,41,42)

InChI Key

SSUZECNFRDBXHC-UHFFFAOYSA-N

Purity

95%+

Application

The purpose of acid-PEG8-S-S-PEG8-acid is to serve as a versatile reactant in various applications involving pegylation and the functionalization of nanoparticles. This compound facilitates the preparation of orthogonally dual-clickable Janus nanoparticles through a cyclic templating strategy, enabling the development of advanced materials with distinct functionalities on each side. Additionally, it is instrumental in the creation of cyclic RGD functionalized gold nanoparticles designed for tumor targeting, contributing to potential breakthroughs in cancer treatments. The asymmetric-functionalization capabilities offered by acid-PEG8-S-S-PEG8-acid support the attachment of specific molecules, enhancing the utility of nanoparticles in biological environments. Furthermore, this compound aids in the functional immobilization of small GTPase Rab6A on DNA-gold nanoparticles through its use as a poly(ethylene glycol) linker in thiol-place exchange reactions. It also plays a crucial role in the direct writing of metal nanoparticle films inside microfluidic channels, allowing biofunctionalization with ligands for protein capture and fluorescence assay, thus expanding possibilities in biochemical analysis and diagnostics.

Complexity

790

Covalently-Bonded Unit Count

Exact Mass

914.421487g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

914.421487g/mol

Rotatable Bond Count

XLogP3

-2.5