Polyester bis-MPA dendron - Materials / Alfa Chemistry

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Polyester bis-MPA dendron

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Catalog Number

ACMA00015872

Product Name

Polyester bis-MPA dendron

Structure

Category

Dendrimers

Synonyms

Bis-MPA dendron, PFd-G4-BocNH-acetylene

Description

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.

Molecular Weight

4317.08

Application

Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s.

Features And Benefits

Polymer architecture: Dendron
Generation: 4
Core functional group: Boc-protected amine
End group functionality: Alkyne
No. surface groups: 16
Calculated mol. wt.: 4317.12 g/mol
Boc: tert-Butyloxycarbonyl
Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

Form

solid

Storage Temperature

−20°C

MSDS

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COA

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Spec Sheet

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