Poly(ethylene glycol) linear dendrimer - Materials / Alfa Chemistry

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Poly(ethylene glycol) linear dendrimer

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Catalog Number

ACMA00015874

Product Name

Poly(ethylene glycol) linear dendrimer

Structure

Category

Dendrimers

Synonyms

PFD-G2-PEG6k-NHBOC, Dendron bifunctionalized PEG

Description

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.

Molecular Weight

8075.40

Application

Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical s.

Features And Benefits

Polymer architecture: Dendron-functionalized PEG
Generation: 2
PEG Average Mn: 6,000
End Group Functionality: Boc-protected amine
No. Surface Groups: 8
Calculated Mol. Wt.: 8075.49 g/mol
Boc: tert-Butyloxycarbonyl
Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

Form

solid

Storage Temperature

−20°C

MSDS

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COA

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Spec Sheet

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