CAS 9004-67-5 Methyl Cellulose (3500-5600mPa·s, 2% in Water at 20°C)

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Methyl Cellulose (3500-5600mPa·s, 2% in Water at 20°C)

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Catalog Number

ACM9004675-1

CAS Number

9004-67-5

Product Name

Methyl Cellulose (3500-5600mPa·s, 2% in Water at 20°C)

Category

Polymers

Description

Methyl cellulose appears as odorless white or creamy white fibrous powder. Tasteless. (NTP, 1992)

IUPAC Name

(5R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

Molecular Weight

454.5g/mol

Molecular Formula

C20H38O11

Canonical SMILES

COCC1C(C(C(C(O1)OC2C(OC(C(C2OC)OC)OC)COC)OC)OC)OC

InChI

InChI=1S/C20H38O11/c1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-8)17(26-6)16(14)25-5/h11-20H,9-10H2,1-8H3/t11?,12?,13?,14-,15?,16?,17?,18?,19?,20+/m1/s1

InChI Key

YLGXILFCIXHCMC-JHGZEJCSSA-N

Melting Point

Decomposes upon heating from 482° F to 572° F (NTP, 1992);290 to 305 °C /Film/

Solubility

5 to 10 mg/mL at 63° F (NTP, 1992);Sol in cold water;Insoluble in alcohol, ether, chloroform, and in water warmer that 50.5 °C; soluble in glacial acetic acid; unaffected by oils and greases.;INSOL IN HOT WATER & MOST ORGANIC SOLVENTS;INSOL IN ALCOHOL, ETHER & CHLOROFORM; SOL IN GLACIAL ACETIC ACID;SOL IN MIXTURE OF EQUAL PARTS OF ALCOHOL & CHLOROFORM; INSOL IN SATURATED SALT SOLN

Application

Methyl Cellulose (3500-5600mPa·s, 2% in Water at 20°C) serves multiple roles across various industries due to its unique properties as a water-soluble, gel-like substance that is both odorless and tasteless. In the food and cosmetic sectors, it acts as a thickener and emulsifier, enhancing product texture and stability. In the realm of advanced cookery, it forms gels and serves as a lubricant. Methyl Cellulose contributes to the treatment of constipation and plays a critical role in capillary electrophoresis as a buffer additive, helping improve separations by controlling electroosmotic flow. In the paper and textile industries, it functions as a sizing agent to protect fibers from moisture and oil. Its applications extend to pharmaceuticals as well, where it is utilized in both oral and topical formulations. In tablets, it is a versatile ingredient, enabling sustained-release preparations, taste masking, and core sealing before sugar coating. As an emulsifier, it is employed in various oil suspensions and helps in delaying the settling of suspensions, thereby extending the contact time of drugs, such as antacids, in the stomach. Methyl Cellulose also thickens products applied topically, like creams and gels, and finds use in ophthalmic and injectable formulations. Therapeutically, it functions as a bulk laxative and has been explored for appetite control, although its efficacy in weight management is not well-supported by evidence.

Color/Form

White granules;White fibrous powders

Complexity

496

Covalently-Bonded Unit Count

Exact Mass

454.241412g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

BFL;Celevac;Cellothyl;Cellulone;Cellulose, Methyl;Citrucel;Cologel;Dacryolarmes;Methocel;Methyl Cellulose;Methylcellulose;Muciplasma

Monoisotopic Mass

454.241412g/mol

Odor

Odorless

Other Experimental

GEL @ TEMP ABOUT 50 °C /AQ SOLN/;STABLE TO ALKALIES & DILUTE ACIDS;Presence of inorganic salts incr viscosity;Swells in water to a viscous colloidal solution. Unaffected by oils and greases. Stable up to approx. 300 °C. Stable to light; combustible. Specifications call for methoxy group content of narrow or wide ranges within 25-33%.;...nonionic and can function as a polymeric surfactant.;Forms high strength films that are clear, water-sol, and oil-and -grease resistant and have low oxygen and moisture vapor transmission rates.;Methyl celluloses have excellent water retention properties.;AVAILABLE IN VISCOSITIES RANGING FROM 10 CP-8000 CP WHEN MEASURED IN 2% SOLN @ 20 °C

Rotatable Bond Count

Stability

STABLE @ ROOM TEMP /AQ SOLN/

Viscosity

10-15,000 cP /2% solution/

XLogP3

-1

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