CAS 9004-67-5 Methyl Cellulose (80-120mPa·s, 2% in Water at 20°C)

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Methyl Cellulose (80-120mPa·s, 2% in Water at 20°C)

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Catalog Number

ACM9004675-4

CAS Number

9004-67-5

Product Name

Methyl Cellulose (80-120mPa·s, 2% in Water at 20°C)

Category

Polymers

Description

Methyl cellulose appears as odorless white or creamy white fibrous powder. Tasteless. (NTP, 1992)

IUPAC Name

(5R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

Molecular Weight

454.5g/mol

Molecular Formula

C20H38O11

Canonical SMILES

COCC1C(C(C(C(O1)OC2C(OC(C(C2OC)OC)OC)COC)OC)OC)OC

InChI

InChI=1S/C20H38O11/c1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-8)17(26-6)16(14)25-5/h11-20H,9-10H2,1-8H3/t11?,12?,13?,14-,15?,16?,17?,18?,19?,20+/m1/s1

InChI Key

YLGXILFCIXHCMC-JHGZEJCSSA-N

Melting Point

Decomposes upon heating from 482° F to 572° F (NTP, 1992);290 to 305 °C /Film/

Solubility

5 to 10 mg/mL at 63° F (NTP, 1992);Sol in cold water;Insoluble in alcohol, ether, chloroform, and in water warmer that 50.5 °C; soluble in glacial acetic acid; unaffected by oils and greases.;INSOL IN HOT WATER & MOST ORGANIC SOLVENTS;INSOL IN ALCOHOL, ETHER & CHLOROFORM; SOL IN GLACIAL ACETIC ACID;SOL IN MIXTURE OF EQUAL PARTS OF ALCOHOL & CHLOROFORM; INSOL IN SATURATED SALT SOLN

Application

Methyl Cellulose (80-120mPa·s, 2% in Water at 20°C) serves a versatile purpose across numerous industries due to its unique properties as a water-soluble, odorless, and tasteless gel-like substance. Primarily, it functions as a thickener and emulsifier in both food and cosmetic products, enhancing texture and stability. In advanced culinary applications, it is used to form gels and acts as a lubricant. Moreover, it plays a crucial role in paper and textile manufacturing, providing a protective sizing that shields fibers from moisture and oil. In pharmaceuticals, its low to medium viscosity grades are essential for binding agents in tablets, assisting in both immediate and sustained-release formulations, as well as taste masking. Additionally, it acts as a disintegrant and coats tablet cores, making it integral to controlled drug release. In liquid formulations, methyl cellulose serves as an emulsifier and thickener, prolonging drug interactions in the gastrointestinal system. Its high-viscosity grades are deployed in topical applications such as creams and gels, and also in certain ophthalmic solutions, though alternatives like hypromellose are preferred today. Beyond these industrial and pharmaceutical applications, methyl cellulose is employed therapeutically as a bulk laxative and has been explored for appetite control in managing obesity, albeit with limited evidence of effectiveness.

Color/Form

White granules;White fibrous powders

Complexity

496

Covalently-Bonded Unit Count

Exact Mass

454.241412g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

BFL;Celevac;Cellothyl;Cellulone;Cellulose, Methyl;Citrucel;Cologel;Dacryolarmes;Methocel;Methyl Cellulose;Methylcellulose;Muciplasma

Monoisotopic Mass

454.241412g/mol

Odor

Odorless

Other Experimental

GEL @ TEMP ABOUT 50 °C /AQ SOLN/;STABLE TO ALKALIES & DILUTE ACIDS;Presence of inorganic salts incr viscosity;Swells in water to a viscous colloidal solution. Unaffected by oils and greases. Stable up to approx. 300 °C. Stable to light; combustible. Specifications call for methoxy group content of narrow or wide ranges within 25-33%.;...nonionic and can function as a polymeric surfactant.;Forms high strength films that are clear, water-sol, and oil-and -grease resistant and have low oxygen and moisture vapor transmission rates.;Methyl celluloses have excellent water retention properties.;AVAILABLE IN VISCOSITIES RANGING FROM 10 CP-8000 CP WHEN MEASURED IN 2% SOLN @ 20 °C

Rotatable Bond Count

Stability

STABLE @ ROOM TEMP /AQ SOLN/

Viscosity

10-15,000 cP /2% solution/

XLogP3

-1

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