CAS 9004-62-0 Hydroxyethyl-cellulose - Materials / Alfa Chemistry

NAVIGATION

Hydroxyethyl-cellulose

PRICE INQUIRY

Catalog Number

ACM9004620-6

CAS Number

9004-62-0

Product Name

Hydroxyethyl-cellulose

Category

Polysaccharide

Description

WHITE POWDER.

IUPAC Name

5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol

Molecular Weight

736.7g/mol

Molecular Formula

(C2H602)x;C29H52O21

Canonical SMILES

CC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)OC)O)O)OC4C(C(C(C(O4)CO)OC)O)OCCO)O)O)O)O

InChI

InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI Key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

Solubility

Solubility in water: good

Application

Hydroxyethyl cellulose is a versatile, nonionic, water-soluble polymer predominantly utilized as a thickening agent in pharmaceutical formulations, particularly in ophthalmic and topical applications. Its role extends to acting as a binder and film-coating agent for tablets, and it is frequently included in lubricant preparations for conditions like dry eye, contact lens care, and dry mouth. The effectiveness of hydroxyethyl cellulose as a thickener, protective colloid, stabilizer, and suspending agent arises from its derivation from wood pulp or chemical cotton, achieved through alkali treatment. This white or off-white, hygroscopic powder offers significant benefits in both pharmaceutical and cosmetic formulations, with its proper concentration in products being contingent upon the solvent and the specific molecular weight grade used.

Complexity

999

Covalently-Bonded Unit Count

EC Number

618-387-5

Exact Mass

736.300109g/mol

Formal Charge

Heavy Atom Count

ICSC Number

1559

MeSH Entry Terms