CAS 7585-39-9 Β-Cyclodextrin - Materials / Alfa Chemistry

NAVIGATION

Β-Cyclodextrin

PRICE INQUIRY

Catalog Number

ACM7585399

CAS Number

7585-39-9

Product Name

Β-Cyclodextrin

Structure

Category

Polysaccharide; Supramolecular Host Materials

Description

DryPowder, Liquid; Liquid;Virtually odourless white or almost white crystalline solid

IUPAC Name

(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecol

Molecular Weight

1134.98

Molecular Formula

C42H70O35

Canonical SMILES

C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O

InChI

InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChI Key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

Purity

98%

Solubility

Sparingly soluble in water; freely soluble in hot water; slightly soluble in ethanol

Appearance

Solid

Application

Β-Cyclodextrin serves as a versatile cyclodextrin commonly used across pharmaceutical, food, and chemical industries due to its ability to form inclusion complexes. This cyclic oligosaccharide is produced naturally from starch through enzymatic conversion and features seven alpha-(1->4) linked D-glucopyranose units. Its unique molecular structure, characterized by a hydrophobic internal cavity and a hydrophilic external surface, allows it to effectively encapsulate various guest molecules. In pharmaceuticals, β-cyclodextrin is primarily employed to enhance the solubility and bioavailability of poorly soluble drugs, mitigate gastrointestinal irritation, and prevent undesirable interactions between drugs and excipients. While being affordable and widely available, it is noteworthy that β-cyclodextrin exhibits nephrotoxicity and should not be used in parenteral formulations. Additionally, it is utilized to mask unpleasant tastes and stabilize formulations in oral tablet and capsule preparations. Beyond pharmaceuticals, β-cyclodextrin finds applications in drug delivery, agriculture, environmental engineering, and the formulation of cosmetics and eye drops, where it enhances drug solubility and stability, reducing irritation and facilitating better absorption.

Storage

Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.

Complexity

1480

Covalently-Bonded Unit Count

EC Number

231-493-2;231-493-2

Exact Mass

1134.369764g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms