Catalog Number
ACM131577-1
Product Name
2-Hydroxy-4-methoxybenzophenone
Category
Plastic Additives; Polymers
Description
2-hydroxy-4-methoxybenzophenone appears as white to off-white or light yellow powder. (NTP, 1992);DryPowder; Liquid;Solid
IUPAC Name
(2-hydroxy-4-methoxyphenyl)-phenylmethanone
Molecular Formula
C14H12O3
Canonical SMILES
COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O
InChI
InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
InChI Key
DXGLGDHPHMLXJC-UHFFFAOYSA-N
Boiling Point
302 to 320 °F at 5 mm Hg (NTP, 1992)
Melting Point
62.00-65.00 °C
Flash Point
100 °C (212 °F) - closed cup
Solubility
less than 1 mg/mL at 68° F (NTP, 1992);In water, 3.7 mg/L at 25 °C;Readily soluble in most organic solvents; freely soluble in alcohol and toluene; practically insoluble in water;Soluble in carbon tetrachloride;Solubility in various solvents (in percent): ethanol, 6%; acetone, >20%; chloroform, >20%; glycerin,<0.01%; isopropyl stearate, 9%; olive oil, 9%; peanut oil, 9%;1.28e-01 g/L
Application
2-Hydroxy-4-methoxybenzophenone serves as a crucial component in sunscreen and cosmetic formulations due to its ability to absorb ultraviolet (UV) radiation. This organic compound, commonly known as oxybenzone, is an FDA-approved UV filter that effectively absorbs both UVB and UVA II rays. By undergoing photochemical excitation, it captures UV energy and emits longer wavelength radiation, thus minimizing skin penetration and reducing the risk of DNA damage. This makes it an essential ingredient for protecting the skin from harmful UV exposure.
Color/Form
Colorless crystals;Crystals from isopropanol;White yellowish, cream colored powder;Pale yellow powder
Covalently-Bonded Unit Count
1
Exact Mass
228.078644g/mol
Log P
3.79 (LogP);log Kow = 3.79;3.79
MeSH Entry Terms
2-hydroxy-4-methoxybenzone;2-hydroxy-4-methoxybenzophenone;benzophenone-3;Eusolex 4360;Eusolex-4360;HMBP cpd;oxybenzone;Solbar
Monoisotopic Mass
228.078644g/mol
Odor
Weak odor;Almost odorless or faint characteristic
Other Experimental
White to off-white powder. /USP/;UV: 939 (Absorption Spectra in the UV and visible Regions, Academic Press, New York) /Benzophenone, 2-hydroxy-4'-methoxy/;MASS: 38922 (NIST/EPA/MSDC Mass Spectral Database, 1990 version) /Benzophenone, 2-hydroxy-4'-methoxy/;UV: 1120 (Absorption Spectra in the UV and visible Regions, Academic Press, New York) /Benzophenone, 2-hydroxy-5-methoxy/;Henry's Law constant = 1.5X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 2.0X10-10 cu cm/molecule-sec at 25 °C (est)
Stability
Stable under recommended storage conditions.;Shelf life: at least 2 years; Stability in distilled water: at least 96 hours; Stability in DMSO: at least 4 hours; Stability in corn oil: at least 10 days; Stability in acetone: at least 3 weeks; Stability in oily lotion: at least 3 weeks.
Vapor Pressure
6.62X10-6 mm Hg at 25 °C (est)