Application
T-Butyldimethylsilane serves multiple purposes in chemical synthesis and protection processes. It is prominently used for protecting hydroxy groups in sugars, a vital step in carbohydrate chemistry. Additionally, its oxidation product, tert-butyldimethylsilyl hydroperoxide, aids in creating luminescent sources and prostanoids such as clavulons. In catalyst chemistry, T-Butyldimethylsilane reacts with an iridium complex to form an active catalyst for the regioselective silylation of various methyl hexopyranosides and related compounds. Furthermore, when used in silylcarbobicyclization reactions with certain catalysts under carbon monoxide pressure, it yields innovative 2-silylbicyclo[3.3.0]octa-1,5-dien-3-ones, demonstrating its versatile role in advancing synthetic methodologies.