CAS 89-00-9 Quinolinic Acid - Materials / Alfa Chemistry

NAVIGATION

Quinolinic Acid

PRICE INQUIRY

Catalog Number

ACM89009

CAS Number

89-00-9

Product Name

Quinolinic Acid

Structure

Category

Monomers

Synonyms

Pyridin-2,3-dicarbonsaeure

Description

DryPowder;Solid

IUPAC Name

Pyridine-2,3-dicarboxylic acid

Molecular Weight

167.12

Molecular Formula

C7H5NO4

Canonical SMILES

C1=CC(=C(N=C1)C(=O)O)C(=O)O

InChI

InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChI Key

GJAWHXHKYYXBSV-UHFFFAOYSA-N

Boiling Point

295.67 °C

Melting Point

188-190 °C(lit.)

Flash Point

210.9 °C

Purity

98%

Density

1.5216 g/cm³

Solubility

Slightly soluble in trifluoroacetic acid, insoluble in ethanol

Appearance

Crystalline powder

Application

Quinolinic acid is a pyridinedicarboxylic acid, presenting itself as either a white or light yellow powder. As an endogenous metabolite of tryptophan, it acts as a potent agonist at N-methyl-D-aspartate (NMDA) receptors, making it a significant excitotoxic compound within the central nervous system. Its interaction with amino acid receptors highlights its importance in understanding human neurodegenerative disorders, potentially linking the functions of kynurenic acid (KYNA) and quinolinic acid (QUIN) in the brain. Additionally, quinolinic acid's properties are utilized in the flotation process of hematite, where it facilitates the selective adsorption of amines onto the hematite surface, demonstrating its versatility beyond biological systems.

Storage

Keep in dark place, sealed in dry, room temperature

Color/Form

Crystals;Monoclinic crystals from water

Complexity

204

Covalently-Bonded Unit Count

EC Number

201-874-8

Exact Mass

167.02185764

Formal Charge

Hazard Statements

Heavy Atom Count

Log P

log Kow = -0.12 (est)

MeSH Entry Terms

Quinolinate;Quinolinic Acid;Quinolinic Acid, Copper(2+) Salt;Quinolinic Acid, Disodium Salt;Quinolinic Acid, Strontium Salt

Monoisotopic Mass

167.02185764

NSC Number

403247;18836;13127

Odor

Odorless

Other Experimental

190 °C when rapidly heated, with decomposition into CO2 and nicotinic acid;Henry's Law constant = 2.86X10-15 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 1.08X10-12 cu cm/molec-sec at 25 °C (est)

Refractive Index

1.628

Rotatable Bond Count

Safety Description

26-36/37-24/25-37

Supplemental Hazard Statements

H315-H319-H335

Topological Polar Surface Area

87.5 Å²

UNII

F6F0HK1URN

Vapor Pressure