Poly(ethylene glycol), 16 acetylene dendron, generation 3

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Catalog Number

ACMA00015943

Product Name

Poly(ethylene glycol), 16 acetylene dendron, generation 3

Category

Dendrimers

Synonyms

PFD-G3-PEG6k-Acetylene, Dendron functionalized PEG acetylene, generation 3, Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, PEG-6000, Bis-MPA poly(ethylene glycol)

Description

Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups. Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life."Clickable groups", such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using "click" chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc.

Molecular Weight

PEG average Mn 6000 (n~130, esterified with 16 acetylene groups)
Mn 7500-9500 (by NMR)
average Mn 8000

Melting Point

43-47 °C

Application

The proposed uses are: as an efficient drug delivery system.
In vitro toxicological studies; In vivo via radionuclide labeling and optical imaging
Biosensors;Dip pen nanolithography

Features And Benefits

acetylene surface groups, generation 3

Packaging

Packaging
500 mg in glass insert

MSDS

Download MSDS

COA

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Spec Sheet

Download Spec Sheet

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