N-Isopropylacrylamide - Materials / Alfa Chemistry

NAVIGATION

N-Isopropylacrylamide

PRICE INQUIRY

Catalog Number

ACMA00017052

Product Name

N-Isopropylacrylamide

Category

Polymers

IUPAC Name

N-propan-2-ylprop-2-enamide

Molecular Weight

113.16g/mol

Molecular Formula

C6H11NO

Canonical SMILES

CC(C)NC(=O)C=C

InChI

InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)

InChI Key

QNILTEGFHQSKFF-UHFFFAOYSA-N

Melting Point

64.0 °C;64 °C

Solubility

In water, 3.077X10+4 mg/L at 25 °C (est);Soluble in water

Application

N-Isopropylacrylamide (NIPAM) serves as a versatile monomer used primarily for creating thermally sensitive polymers, such as poly(N-isopropylacrylamide) (pNIPAM)-based hydrogels. This compound is key in producing stimuli-responsive materials, thanks to its unique temperature-sensitive properties. Specifically, these polymers exhibit significant volumetric and phase changes when the temperature exceeds 33°C, known as the lower critical solution temperature (LCST). The biocompatible nature of NIPAM allows it to be employed in numerous applications, including tissue engineering, cell culture, biomedical coatings, drug delivery, and muscle regeneration, providing dynamic functionality in various fields.

Color/Form

Crystalline solid;Cream-colored powder

Complexity

96.7

Covalently-Bonded Unit Count

EC Number

218-638-5

Exact Mass

113.084064g/mol

Formal Charge

Heavy Atom Count

Log P

log Kow = 0.57 (est)

MeSH Entry Terms

N-isopropylacrylamide

Monoisotopic Mass

113.084064g/mol

NSC Number

11448

Other Experimental

BP: 89-92 °C at 2 mm Hg; VP: 2 mm Hg at 83 °C; Storage temp: 2-8 °C;Acrylic resins vary from hard, brittle solids to fibrous, elastomeric structures to viscous liquids, depending on the monomer used and the method of polymerization. A distinctive property of cast sheet and extruded rods of acrylic resins is ability to transmit light /Acrylic resins/;Henry's Law constant = 2.28X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 2.30X10-11 cu cm/molec-sec at 25 °C (est);Ozone radical reaction rate constant = 1.8X10-18 cu cm/molecule-sec at 25 °C (est)

Rotatable Bond Count

Stability

Stable under recommended storage conditions.

UNII

B7GFF17L9U

Vapor Pressure

2.32X10-2 mm Hg at 25 °C (est)

XLogP3

0.9

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