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Glycolic Acid, Crystal, Reagent

Name: Glycolic Acid, Crystal, Reagent
SKU: ACM79141-1
Rating: 5 (1 reviews)

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Catalog NumberACM79141-1

CAS Number79-14-1

CategoryPolymers

Description

DryPowder; Liquid; PelletsLargeCrystals;Solid;COLOURLESS HYGROSCOPIC CRYSTALS.

IUPAC Name

2-hydroxyacetic acid

Molecular Weight

76.05g/mol

Molecular Formula

C2H4O3;HOCH2COOH;C2H4O3

Canonical SMILES

C(C(=O)O)O

InChI

InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI Key

AEMRFAOFKBGASW-UHFFFAOYSA-N

Boiling Point

100 °C

Melting Point

79.5 °C;78-80 °C (alpha-modification); 63 °C (beta-modification, metastable);75-80°C;80 °C

Density

1.49 at 25 °C/4 °C;Relative density (water = 1): 1.49

Solubility

In water, 1X10+6 mg/L at 25 °C (est);Soluble in ethanol, ethyl ether;Soluble in methanol, acetone, acetic acid;Solubility in water: very good

Application

Glycolic Acid, Crystal, Reagent serves a versatile purpose across various industries, primarily in skincare. As the smallest alpha-hydroxy acid (AHA), its molecular structure allows for deep penetration into the skin, making it highly effective in exfoliating and enhancing skin hydration. It dissolves the cellular cement responsible for excessive keratinization, promoting the sloughing of dead skin cells and reducing common skin issues like acne, dry skin, and wrinkles. Its ability to enhance moisture uptake and improve skin's water binding capacity further elevates its role in skincare, leading to softer, smoother, and younger-looking skin. Beyond cosmetics, glycolic acid is utilized in the textile industry for dyeing and tanning, as a flavoring agent in food processing, and in pharmaceuticals. Additionally, it is integrated into emulsion polymers, solvents, and ink additives to improve flow properties and add gloss. Glycolic acid is also a key intermediate in organic synthesis, including reactions like oxidative-reduction, esterification, and polymerization, making it indispensable in both industrial and cosmetic applications.

Color/Form

Colorless, translucent solid;Solid glycolic acid forms colorless, monoclinic, prismatic crystals.;Orthorhombic needles from water; leaves from diethyl ether

Complexity

40.2

Corrosivity

Corrosive

Covalently-Bonded Unit Count

EC Number

201-180-5;217-693-2;247-326-1

Exact Mass

76.016044g/mol

Formal Charge

Heavy Atom Count

ICSC Number

1537

Log P

-1.11 (LogP);log Kow = -1.11;-1.11;-1.11

MeSH Entry Terms

glycolate;glycolic acid;glycolic acid, 1-(14)C-labeled;glycolic acid, 2-(14)C-labeled;glycolic acid, calcium salt;glycolic acid, monoammonium salt;glycolic acid, monolithium salt;glycolic acid, monopotassium salt;glycolic acid, monosodium salt;glycolic acid, potassium salt;hydroxyacetic acid;potassium glycolate

Monoisotopic Mass

76.016044g/mol

NSC Number

166

Odor

Odorless

Other Experimental

BP: decomposes;MP: 79.5 °C;Hygroscopic;Heat of combustion: 697.1kJ/mole; heat of solution: -11.5 kJ/mole;Light, straw-colored lliquid, odor like burnt sugar; density: 1.27; mp: 10 °C /Commercial 70% solution/;When heated to decomposition it emits acrid smoke and irritating fumes.;Henry's Law constant = 8.5X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 3.11X10-12 cu cm/molecule-sec at 25 °C (est)

Rotatable Bond Count

RTECS Number

MC5250000

Stability

Stable under recommended storage conditions.

UNII

0WT12SX38S

UN Number

3261

Vapor Density

Relative vapor density (air = 1): 2.6

Vapor Pressure