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Dextran sulfate sodium salt from Leuconostoc spp.

Name: Dextran sulfate sodium salt from Leuconostoc spp.
SKU: ACM9011181
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Catalog NumberACM9011181

CAS Number9011-18-1

CategoryNatural Polymers and Biopolymers; Polysaccharide

Description

DryPowder;Solid

IUPAC Name

ethyl 4-aminobenzoate

Molecular Weight

165.19g/mol

Molecular Formula

C9H11NO2

Canonical SMILES

CCOC(=O)C1=CC=C(C=C1)N

InChI

InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

InChI Key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

Boiling Point

310.0 °C;310 °C

Melting Point

92.0 °C;92 °C;92°C

Solubility

0.01 M;One gram dissolves in about 5 ml alcohol, 2 ml chloroform, in about 4 ml ether, and in 30 to 50 ml of expressed almond oil or olive oil. Also sol in dil acids.;Soluble in acid;In water, 1,310 mg/L at 25 °C;>24.8 [ug/mL]

Application

Dextran sulfate sodium salt derived from Leuconostoc spp. serves a versatile role in scientific research and applications. This white to off-white powder is effectively utilized in a range of electrophoretic techniques, such as polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE) and agarose gel electrophoresis for RNA. It is also incorporated into SPOTs imaging for sequential probing of targets and acts as a component in certain injection buffers. Notably, dextran sulfate sodium salt has been explored for its anticoagulant properties, demonstrating potential as a substitute for heparin, with particular interest in its interactions with enzyme and inhibitor systems within the coagulation cascade. Furthermore, when immobilized on cellulose, it can selectively remove LDL cholesterol during plasmapheresis. Its broad spectrum of biological activities includes enzyme inhibition, immune response modulation, cell interaction influences, and effects on viral infectivity, making it an attractive compound for further scientific inquiry.

Color/Form

Rhombohedra from ether;Needles from water

Complexity

151

Covalently-Bonded Unit Count

EC Number

202-303-5;618-471-1

Exact Mass

165.078979g/mol

Formal Charge

Heavy Atom Count

Log P

1.86 (LogP);log Kow = 1.86;1.86

MeSH Entry Terms

4-Aminobenzoic Acid Ethyl Ester;Acetate, Benzocaine;Americaine;Anaesthesin;Anesthesin;Bensokain;Benzocaine;Benzocaine Acetate;Benzocaine Formate;Benzocaine Hydrobromide;Benzocaine Hydrochloride;Benzocaine Methanesulfonate;Ethoform;Ethyl Aminobenzoate;Formate, Benzocaine;Hydrobromide, Benzocaine;Hydrochloride, Benzocaine;Methanesulfonate, Benzocaine

Monoisotopic Mass

165.078979g/mol

NSC Number

755909;41531;4688

Other Experimental

Stable in air;Henry's Law constant = 1.6X10-8 atm-cu m/mole at 25 °C /Estimated/;Hydroxyl radical reaction rate constant = 3.6X10-11 cu cm/molecule-sec at 25 °C /Estimated/

Rotatable Bond Count

RTECS Number

DG2450000

Stability

Stable in air.

UNII

U3RSY48JW5

Vapor Pressure

2.6X10-4 mm Hg at 25 °C /Estimated/

XLogP3

1.9

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