CAS 1833-51-8 (Chloromethyl)Dimethylphenylsilane

NAVIGATION

(Chloromethyl)Dimethylphenylsilane

PRICE INQUIRY

Catalog Number

ACM1833518

CAS Number

1833-51-8

Product Name

(Chloromethyl)Dimethylphenylsilane

Structure

Category

Salt

Synonyms

chloromethyl-phenyldimethylsilane; dimethylphenylchloromethylsilane; (dimethylphenylsilyl)-methyl chloride; (Chloromethyl)dimethyl(phenyl)silane; PhMe2SiCH2Cl; Dichloromethyldimethylphenylsilane; Phenyldimethyl(chloromethyl)silane; Me2PhSiCH2Cl; ChloroMethyldiMethylphenylsilane; (Chloromethyl)dimethylphenylsilane; Silane,(chloromethyl)dimethylphenyl;

IUPAC Name

chloromethyl-dimethyl-phenylsilane

Molecular Weight

184.73 g/mol

Molecular Formula

C9H13ClSi

Boiling Point

223.8ºC at 760mmHg

Flash Point

91.1ºC

Purity

95%+

Density

0.99g/cm³

Appearance

Transparent liquid

Application

(Chloromethyl)dimethylphenylsilane is primarily utilized as a versatile starting material in organic synthesis Initially reported in 1949 its main use was to convert into corresponding Grignard reagents Over time its applications have broadened to include heteroatom and carbon alkylation as well as the formation of various organometallic and organolanthanide reagents One of its distinct advantages over similar compounds like (chloromethyl)trimethylsilane is its capacity for Fleming oxidation which allows it to act as a masked hydroxyl group This property is especially useful for creating C- and N-substituted adducts However users must be cautious of its tendency to rearrange under certain conditions Additionally (chloromethyl)dimethylphenylsilane serves as a precursor for synthesizing (phenyldimethylsilyl)methoxymethyl chloride a hydroxyl protecting group known as SMOM-Cl It is effectively employed in the silylmethyl group installation on carbon through base-promoted C-alkylation working well with substrates like terminal alkynes dihydropyrazines malonic esters phenylacetonitriles sulfoxides and imines Occasionally conversion to its iodide form is preferred before alkylation These transformations typically require strong basic conditions and careful temperature control

Exact Mass

184.04800

Hazard Statements

Xi: Irritant;

Packaging

10 g; 100 g;

Safety Description

26-36

WGK Germany

MSDS

Download MSDS

COA