CAS 7585-39-9 beta-Cyclodextrin - Materials / Alfa Chemistry

NAVIGATION

beta-Cyclodextrin

PRICE INQUIRY

Catalog Number

ACM7585399-3

CAS Number

7585-39-9

Product Name

beta-Cyclodextrin

Structure

Category

Macrocycles

Synonyms

Cycloheptapentylose

Description

DryPowder, Liquid; Liquid;Virtually odourless white or almost white crystalline solid

IUPAC Name

(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecol

Molecular Weight

1135g/mol

Molecular Formula

C42H70O35

Canonical SMILES

C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O

InChI

InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChI Key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

Boiling Point

845°C

Melting Point

290-300 °C (dec.) (lit.)

Flash Point

908.5°C

Density

1.23g/ml

Solubility

Sparingly soluble in water; freely soluble in hot water; slightly soluble in ethanol

Appearance

White powder

Application

Beta-Cyclodextrin serves as a versatile compound with a wide range of applications across various industries. It is a cyclic oligosaccharide derived from starch through an enzymatic conversion process, resulting in a crystalline solid or fine powder. This cyclic structure, composed of seven D-glucopyranose units, forms a toroid shape with a hydrophobic internal cavity and a hydrophilic external surface. Such an arrangement allows beta-cyclodextrin to encapsulate guest molecules, enhancing their solubility and stability. This property is particularly beneficial in pharmaceuticals, where it is employed to improve the solubility, bioavailability, and stability of poorly soluble drugs, mitigate gastrointestinal irritation, and prevent drug interactions. Despite being the least soluble cyclodextrin, it is the most widely used due to its cost-effectiveness and the ability to form inclusion complexes with a variety of molecules of pharmaceutical interest. However, its use is limited to non-parenteral formulations due to nephrotoxicity risks. Beyond pharmaceuticals, beta-cyclodextrin is utilized in food, chemical, agricultural, and environmental applications, demonstrating its broad utility in enhancing substance properties and delivery.

Assay

0.999

Complexity

1480

Covalently-Bonded Unit Count

EC Number

231-493-2;231-493-2

Exact Mass

1134.369764g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms