CAS 83-73-8 5,7-Diiodo-8-hydroxyquinoline - Materials / Alfa Chemistry

NAVIGATION

5,7-Diiodo-8-hydroxyquinoline

PRICE INQUIRY

Catalog Number

ACM83738

CAS Number

83-73-8

Product Name

5,7-Diiodo-8-hydroxyquinoline

Structure

Category

Ligands for Functional Metal Complexes

IUPAC Name

5,7-diiodoquinolin-8-ol

Molecular Weight

396.95g/mol

Molecular Formula

C9H5I2NO

Canonical SMILES

C1=CC2=C(C(=C(C=C2I)I)O)N=C1

InChI

InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

InChI Key

UXZFQZANDVDGMM-UHFFFAOYSA-N

Melting Point

210.0 °C;MP 200-215 °C WITH EXTENSIVE DECOMP

Purity

97%

Solubility

ALMOST INSOL IN WATER; SPARINGLY SOL IN ALCOHOL, ETHER, ACETONE; SOL IN HOT PYRIDINE & HOT DIOXANE

Appearance

Yellow to Tan
Powder or Crystals

Application

5,7-Diiodo-8-hydroxyquinoline serves primarily as an amoebicidal agent utilized in the treatment of infections such as amoebiasis and balantidiasis, which are caused by protozoa. It is recognized as the preferred medication for addressing asymptomatic or moderate forms of amoebiasis. This compound plays multiple roles, functioning as an antiamoebic, antibacterial, antiseptic, and antiprotozoal agent. While it is effective for treating both acute and chronic intestinal amebiasis, it is not suitable for treating extraintestinal diseases. Notably, due to its relatively high risk of causing optic neuropathy, it is not recommended for routine use in managing traveler's diarrhea. This yellowish to tan, light-sensitive, microcrystalline substance is also known by other names such as 5,7-diiodo-8-quinolinol, diiodohydroxyquin, Yodoxin, Diodoquin, and Diquinol.

Color/Form

CRYSTALS FROM XYLENE; MEDICINAL GRADE IS YELLOWISH-BROWN POWDER;ABOVE 150 DEG, SUBLIMATES OF NEEDLES, PRISMS & RODS; ABOVE 200 DEG BROWN DROPS; MELT TURNS DARK-BROWN;LIGHT YELLOWISH TO TAN, MICROCRYSTALLINE POWDER

Complexity

191

Covalently-Bonded Unit Count

EC Number

201-497-9

Exact Mass

396.84606g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

Diiodohydroxyquin;Diiodohydroxyquinoline;Diiodoquin;Diodoquin;Diodoxyquinoline;Diquinol;Entero Diyod;Entero-Diyod;EnteroDiyod;Entodiba;Iodoquinol;Sebaquin;Yodoxin

Monoisotopic Mass

396.84606g/mol

NSC Number

757077;8704

Odor

ODORLESS OR NEARLY SO

Rotatable Bond Count

Stability

STABLE IN AIR

UNII

63W7IE88K8

XLogP3