Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

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Biomaterials

Biodegradable Polymers

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

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Catalog Number

ACMA00003230

Product Name

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

Structure

Category

Biodegradable Polymers

Synonyms

PLGA-PEG-PLGA

Description

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Molecular Weight

PEG average Mn 1,000
PLGA average Mn 2,200
average Mn (1100-1000-1100)

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features And Benefits

Good biocompatibility, low immunogenicity and good degradability.
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Packaging

1 g in glass bottle

Storage Temperature

2-8°C

MSDS

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COA

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Spec Sheet

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