NAVIGATION
Patel, Jwala, et al. RSC advances, 2020, 10(45), 27103-27136.
Xanthan Gum (XG) is known for its biocompatibility, non-toxicity and biodegradability. Further chemical modification of xanthan gum can break through its own limitations, and the obtained xanthan gum derivatives can meet the diverse needs of drug delivery, tissue engineering, oil drilling and other applications.
Synthesis of modified xanthan gum materials
· Etherified XG: The most common and widely studied XG ether derivative is O-carboxymethyl XG.
· Esterified XG: XG has also been reshaped through esterification. For example, esterification of the carboxyl group of XG with 1-bromooctane promotes hydrophobic association, thereby increasing the viscosity of XG.
· Oxidation of XG: Oxidation of XG can partially convert the glucopyranose units into aldehydes and create additional functional sites for covalent cross-linking.
· Amide Functionalized XG: The carboxyl functionality of the XG chain may be the focal point for bifunctional amine cross-linkers to establish covalent amide bonds.
· Acetal XG: The properties of XG can be modified by the formation of acetal bonds in the presence of aldehydes.
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