CAS 22199-08-2 Silver sulfadiazine - Materials / Alfa Chemistry

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Silver sulfadiazine

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Catalog Number

ACM22199082

Product Name

Silver sulfadiazine

Structure

CAS

22199-08-2

Category

Electrolytes

Synonyms

4-Amino-n-2-pyrimidinylbenzenesulfonamide monosilver salt

Description

Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication.

IUPAC Name

Silver;(4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide

Molecular Weight

357.14

Molecular Formula

C10H9AgN4O2S

Canonical SMILES

C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Ag+]

InChI

InChI=1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI Key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

Melting Point

285 °C

Purity

99%+

Appearance

White to off-white powder

Storage

Keep in dark place,inert atmosphere,Room temperature

Complexity

327

Covalently-Bonded Unit Count

EC Number

244-834-5

Exact Mass

355.94971

Formal Charge

Heavy Atom Count

MeSH Entry Terms

Brandiazin;Dermazin;Flamazine;Flammazine;Sicazine;Silvadene;Silvederma;Silver Sulfadiazine;Silver Sulfafdiazine;SSD;SSD AF;Sulfadiazine, Silver;Sulfafdiazine, Silver;Sulfargen;Thermazene

Monoisotopic Mass

355.94971

Rotatable Bond Count

Topological Polar Surface Area

95.3 Å²

UNII

W46JY43EJR

MSDS

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COA

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Spec Sheet