Catalog Number
ACM22199082
Product Name
Silver sulfadiazine
Synonyms
4-Amino-n-2-pyrimidinylbenzenesulfonamide monosilver salt
Description
Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication.
IUPAC Name
Silver;(4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
Molecular Formula
C10H9AgN4O2S
Canonical SMILES
C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Ag+]
InChI
InChI=1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
InChI Key
UEJSSZHHYBHCEL-UHFFFAOYSA-N
Appearance
White to off-white powder
Storage
Keep in dark place,inert atmosphere,Room temperature
Covalently-Bonded Unit Count
2
MeSH Entry Terms
Brandiazin;Dermazin;Flamazine;Flammazine;Sicazine;Silvadene;Silvederma;Silver Sulfadiazine;Silver Sulfafdiazine;SSD;SSD AF;Sulfadiazine, Silver;Sulfafdiazine, Silver;Sulfargen;Thermazene
Monoisotopic Mass
355.94971
Topological Polar Surface Area
95.3 Ų