CAS 31852-29-6 Polyinosinic-polycytidylic acid potassium salt

NAVIGATION

Polyinosinic-polycytidylic acid potassium salt

PRICE INQUIRY

Catalog Number

ACM31852296-1

CAS Number

31852-29-6

Product Name

Polyinosinic-polycytidylic acid potassium salt

Structure

Category

Oligonucleotide Polymers and Copolymers

Synonyms

POLY[I] POLY[C] POTASSIUM SALT;POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT;Polyinosinic acid . Polycytidylic acid potassium salt;polyinosinic-polycytidylic acid*potassium;polyinosinic acid/ polycytidylic potassium;Poly I:C PotassiuM Salt;5-Cytidylic ac

Molecular Weight

710.5g/mol

Molecular Formula

C19H27KN7O16P2

Canonical SMILES

C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O.[K]

InChI

InChI=1S/C10H13N4O8P.C9H14N3O8P.K/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);/t4-,6-,7-,10-;4-,6-,7-,8-;/m11./s1

InChI Key

KHPUABRWHJGXNJ-VRQAYDGLSA-N

Purity

96%

Appearance

Lyophilized powder

Application

Polyinosinic-polycytidylic acid potassium salt serves as a tool to activate the immune response by mimicking viral double-stranded RNA, thereby enabling the study of cellular signaling through Toll-like receptor 3 (TLR3). As a TRIF-dependent TLR3 ligand, it is instrumental in research focused on understanding the mechanisms of immune response against viral pathogens. By engaging TLR3, Poly(IC) provides valuable insights into the complex pathways of the immune system's reaction to viral infections.

Complexity

1090

Covalently-Bonded Unit Count

Exact Mass

710.062658g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

710.062658g/mol

Rotatable Bond Count

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