CAS 26936-41-4 POLYINOSINIC ACID (5') POTASSIUM SALT

NAVIGATION

POLYINOSINIC ACID (5') POTASSIUM SALT

PRICE INQUIRY

Catalog Number

ACM26936414-1

CAS Number

26936-41-4

Product Name

POLYINOSINIC ACID (5') POTASSIUM SALT

Category

Oligonucleotide Polymers and Copolymers

IUPAC Name

potassium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl hydrogen phosphate

Molecular Weight

386.3g/mol

Molecular Formula

C10H12KN4O8P

Canonical SMILES

C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)[O-])O)O.[K+]

InChI

InChI=1S/C10H13N4O8P.K/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

InChI Key

AWOLVHQZOSVDSL-MCDZGGTQSA-M

Application

POLYINOSINIC ACID (5') POTASSIUM SALT serves as a crucial component in studying immune responses, particularly through its role in forming the double-stranded homopolymer with polycytidylic acid (poly(C)), known as Poly(I) · Poly(C). This compound is instrumental for research involving toll-like receptor-3 (TLR3), which is known to recognize double-stranded RNA and plays a key role in the immune system's response to viral infections. By acting as a model RNA, POLYINOSINIC ACID (5') POTASSIUM SALT facilitates the investigation of cell signaling pathways at the level of TLR3, contributing to a deeper understanding of the mechanisms underpinning innate immunity.

Complexity

567

Covalently-Bonded Unit Count

Exact Mass

386.002982g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

386.002982g/mol

Rotatable Bond Count

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