CAS 26124-68-5 Polyglycolide - Materials / Alfa Chemistry

NAVIGATION

Polyglycolide

PRICE INQUIRY

Catalog Number

ACM26124685-2

CAS Number

26124-68-5

Product Name

Polyglycolide

Category

Biodegradable Polymers

Synonyms

PGA, Poly(glycolic acid)

Description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

IUPAC Name

2-hydroxyacetic acid

Molecular Weight

76.05g/mol

Molecular Formula

(C2H4O3)n

Canonical SMILES

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI Key

AEMRFAOFKBGASW-UHFFFAOYSA-N

Boiling Point

100 °C

Melting Point

79.5 °C;78-80 °C (alpha-modification); 63 °C (beta-modification, metastable);75-80°C;80 °C

Density

1.53 g/mL at 25 °C (lit.)

Solubility

In water, 1X10+6 mg/L at 25 °C (est);Soluble in ethanol, ethyl ether;Soluble in methanol, acetone, acetic acid;Solubility in water: very good

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.

Color/Form

Colorless, translucent solid;Solid glycolic acid forms colorless, monoclinic, prismatic crystals.;Orthorhombic needles from water; leaves from diethyl ether

Complexity

40.2

Corrosivity

Corrosive

Covalently-Bonded Unit Count

EC Number

201-180-5;217-693-2;247-326-1

Exact Mass

76.016044g/mol

Features And Benefits

Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

Formal Charge

Heavy Atom Count

ICSC Number

1537

Log P

-1.11 (LogP);log Kow = -1.11;-1.11;-1.11

MDL Number

MFCD00148011

MeSH Entry Terms

glycolate;glycolic acid;glycolic acid, 1-(14)C-labeled;glycolic acid, 2-(14)C-labeled;glycolic acid, calcium salt;glycolic acid, monoammonium salt;glycolic acid, monolithium salt;glycolic acid, monopotassium salt;glycolic acid, monosodium salt;glycolic acid, potassium salt;hydroxyacetic acid;potassium glycolate

Monoisotopic Mass

76.016044g/mol

NSC Number

166

Odor

Odorless

Other Experimental

BP: decomposes;MP: 79.5 °C;Hygroscopic;Heat of combustion: 697.1kJ/mole; heat of solution: -11.5 kJ/mole;Light, straw-colored lliquid, odor like burnt sugar; density: 1.27; mp: 10 °C /Commercial 70% solution/;When heated to decomposition it emits acrid smoke and irritating fumes.;Henry's Law constant = 8.5X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 3.11X10-12 cu cm/molecule-sec at 25 °C (est)

Packaging

1, 5, 10 g in glass bottle

Rotatable Bond Count

RTECS Number

MC5250000

Stability

Stable under recommended storage conditions.

Storage Temperature

2-8°C

UNII

0WT12SX38S

UN Number