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Polyethylene Glycol 300

Catalog Number
ACM25322683-44
CAS Number
25322-68-3
Product Name
Polyethylene Glycol 300
Structure
Category
Polymers
Application
Polyethylene Glycol 300 is a versatile polymer designed to serve multiple functions in pharmaceutical and biotechnological applications. It is a liquid form of polyethylene glycol obtained by the polymerization of ethylene oxide and water, resulting in a clear, colorless, or slightly yellow viscous liquid with a mild odor. Its unique solubility properties make it an ideal choice for use as a solvent in soft gelatin capsules and as a vehicle in parenteral dosage forms at concentrations of up to 30% v/v. PEG 300 enhances the solubility and dissolution characteristics of poorly soluble compounds through its ability to form solid dispersions. Owing to its hydrophilic nature and stability, PEG 300 is widely utilized in controlled-release systems, showcasing its compatibility with various pharmaceutical formulations like oral, ophthalmic, topical, and rectal preparations. Its use extends to being a viscosity adjuster, emulsion stabilizer, and plasticizer in film coatings. Despite its myriad applications, care must be taken in its use due to its higher chemical reactivity compared to fats, particularly in formulations like suppositories and microencapsulated products.
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