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  • Poly(ethylene glycol) and Poly(ethylene oxide)
  • Poly(ethylene glycol) (N-hydroxysuccinimide 5-pentanoate) ether 2-(biotinylamino)ethane

  • Poly(ethylene glycol) (N-hydroxysuccinimide 5-pentanoate) ether 2-(biotinylamino)ethane

    Catalog Number
    ACMA00013952
    Product Name
    Poly(ethylene glycol) (N-hydroxysuccinimide 5-pentanoate) ether 2-(biotinylamino)ethane
    Category
    Poly(ethylene glycol) and Poly(ethylene oxide)
    Synonyms
    Biotin-PEG, Poly(ethylene glycol) (N-hydroxysuccinimide acetic acid) ether biotin, protected valeric acid, biotin carboxylic acid PEG, NHS - protected acid PEG, Biotin polyoxyethylene maleimide, Biotin-PEG maleimide, Biotinylated PEG
    Description
    Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
    Molecular Weight
    PEG average Mn 3,400 (n ~ 77)
    average Mn 3,800
    Melting Point
    45-53 °C
    Application
    Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
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    Packaging
    Packaging
    100 mg in glass insert
    Storage Temperature
    −20°C
    If you have any other questions or need other size, please get a quote.
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