Poly(ethylene glycol) methyl ether 2-(dodecylthiocarbonothioylthio)-2-methylpropionate

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Catalog Number

ACMA00049742

Product Name

Poly(ethylene glycol) methyl ether 2-(dodecylthiocarbonothioylthio)-2-methylpropionate

Category

Polyethylene (PE)

Synonyms

Methoxy poly(ethylene oxide)-2-(dodecylthiocarbonothioylthio)-2-methylpropionate, PEG DDMAT macroCTA

Description

Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.

Molecular Weight

average Mn 1,100

Application

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

Features And Benefits

1. High quality products
2. Fast delivery
3. Additional products can be ordered, please contact us for details

Form

liquid
semisolid
solid

Packaging

Packaging
1 g in glass bottle

Personal Protective Equipment

Eyeshields, full-face respirator, gloves, multi-purpose combination respirator cartridge, type ABEK (EN14387) respirator filter

Sensitivity

Heat sensitive

MSDS

Download MSDS